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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSF
All Species:
29.7
Human Site:
T19
Identified Species:
46.67
UniProt:
P46459
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46459
NP_006169.2
744
82594
T19
P
T
D
E
L
S
L
T
N
C
A
V
V
N
E
Chimpanzee
Pan troglodytes
XP_511626
842
92301
T92
P
T
D
E
L
S
L
T
N
C
A
V
V
N
E
Rhesus Macaque
Macaca mulatta
XP_001105450
854
93325
T129
P
T
D
E
L
S
L
T
N
C
A
V
V
N
E
Dog
Lupus familis
XP_548044
752
83541
T19
P
T
D
E
L
S
L
T
N
C
A
V
V
N
E
Cat
Felis silvestris
Mouse
Mus musculus
P46460
744
82595
S19
P
T
D
E
L
S
L
S
N
C
A
V
V
N
E
Rat
Rattus norvegicus
Q9QUL6
744
82634
S19
P
T
D
E
L
S
L
S
N
C
A
V
V
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418094
740
82158
T19
P
T
D
E
L
S
L
T
N
C
A
V
V
N
D
Frog
Xenopus laevis
P23787
805
89193
Q19
L
S
T
A
I
L
K
Q
K
S
R
P
N
R
L
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
Q19
L
S
T
A
I
L
K
Q
K
N
R
P
N
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46461
745
82537
N19
T
D
E
L
S
L
T
N
R
A
I
V
N
V
G
Honey Bee
Apis mellifera
XP_001120201
743
82591
N20
T
D
E
L
S
I
T
N
C
A
I
I
N
P
D
Nematode Worm
Caenorhab. elegans
Q94392
824
91316
Y83
E
E
H
T
L
A
N
Y
A
Y
V
N
R
S
D
Sea Urchin
Strong. purpuratus
NP_999752
746
82671
N21
T
D
Q
L
S
L
T
N
R
A
V
V
S
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0Y8
742
81469
A28
D
L
A
F
T
N
L
A
Y
C
S
S
S
D
L
Baker's Yeast
Sacchar. cerevisiae
P18759
758
84038
S38
V
S
N
C
P
N
N
S
Y
A
L
A
N
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
86.8
98.1
N.A.
98.1
97.8
N.A.
N.A.
93.6
26.2
25
N.A.
62.4
65.8
50.6
64.8
Protein Similarity:
100
88.2
87.1
98.8
N.A.
99.7
99.7
N.A.
N.A.
96.5
44.2
44.4
N.A.
77.7
81.1
66.2
80.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
0
0
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
13.3
N.A.
13.3
20
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.6
64.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
14
0
7
0
7
7
27
47
7
0
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
7
54
0
0
0
0
0
% C
% Asp:
7
20
47
0
0
0
0
0
0
0
0
0
0
14
20
% D
% Glu:
7
7
14
47
0
0
0
0
0
0
0
0
0
0
40
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
14
7
0
0
0
0
14
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
14
0
14
0
0
0
0
0
7
% K
% Leu:
14
7
0
20
54
27
54
0
0
0
7
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
14
14
20
47
7
0
7
34
47
0
% N
% Pro:
47
0
0
0
7
0
0
0
0
0
0
14
0
7
0
% P
% Gln:
0
0
7
0
0
0
0
14
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
14
0
14
0
7
14
0
% R
% Ser:
0
20
0
0
20
47
0
20
0
7
7
7
14
7
0
% S
% Thr:
20
47
14
7
7
0
20
34
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
14
60
47
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
14
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _